I have made a bit of progress and hit another wall.
By the way, I am following instructions in James Foxall's "Sams Teach Yourself Visual Basic 2010 in 24 hours." In the beginning of the book, he says he used Express for everything in the book.
Hour (chapter) 23 is titled, Deploying Applications. It steps through using ClickOnce technology to create a ClickOnce application. After he creates it with his simple demo app, he then runs the setup.exe to install the application. I am able to create the ClickOnce without a problem. When I take it to another machine to install it, the install runs smoothly then presents this long message, "Unable to install or run the application. The application requires that assembly Microsoft.VisualBasic.PowerPacks.Vs Version 10.0.0.0 be installed in the Global Assembly Cache (GAC) first. Please contact your system administrator."
To answer your question about the files in the Release folder, here's the whole thing...
Application Files (folder)
In all cases, MyApp, is the name of my application, which I an not permitted to show here.